BS

GON4L

GON-4-liki protein jest protein koji je kod ljudikodirangenomGON4L sa hromosoma 1.[5][6] To je jedarni protein koji sadrži dva serinskog fosfozita i poprečnu vezu lizinglutamin[7] i smatra se da je transkripcijski faktor.[8]

GON4L
Dostupne strukture
PDB Pretraga ortologa: PDBeRCSB
Spisak PDB ID kodova

1UG2

Identifikatori
Aliasi GON4L
Vanjski ID-jevi OMIM: 610393MGI: 1917579HomoloGene: 13002GeneCards: GON4L
Lokacija gena (čovjek)
Hrom. Hromosom 1 (čovjek)[1]

Bend 1q22 Početak 155,749,659 bp[1]
Kraj 155,859,400 bp[1]
Lokacija gena (miš)
Hrom. Hromosom 3 (miš)[2]

Bend 3|3 F1 Početak 88,835,231 bp[2]
Kraj 88,910,103 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija DNA binding
GO:0001106 transcription corepressor activity
GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific
Ćelijska komponenta Nukleoplazma
nuclear body
Jedro
Biološki proces transcription, DNA-templated
regulation of transcription, DNA-templated
B cell differentiation
negative regulation of transcription, DNA-templated
regulation of transcription by RNA polymerase II
Izvori:Amigo / QuickGO
Ortolozi
Vrste Čovjek Miš
Entrez

54856

76022

Ensembl

ENSG00000116580

ENSMUSG00000054199

UniProt

Q3T8J9

Q9DB00

RefSeq (mRNK)
NM_001037533
NM_001282856
NM_001282858
NM_001282860
NM_001282861

NM_032292
NM_025174

NM_001242372
NM_027389

RefSeq (bjelančevina)

NP_001269785
NP_001269787
NP_001269789
NP_001269790
NP_115668

NP_001229301
NP_081665

Lokacija (UCSC) Chr 1: 155.75 – 155.86 Mb Chr 3: 88.84 – 88.91 Mb
PubMed pretraga [3] [4]
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

. . . GON4L . . .

Dužina polipeptidnog lanca je 2.241 aminokiselina, a molekulska težina 248.620 Da. [9]

10 20 30 40 50
MLPCKKRRTT VTESLQHKGN QEENNVDLES AVKPESDQVK DLSSVSLSWD
PSHGRVAGFE VQSLQDAGNQ LGMEDTSLSS GMLTQNTNVP ILEGVDVAIS
QGITLPSLES FHPLNIHIGK GKLHATGSKR GKKMTLRPGP VTQEDRCDHL
TLKEPFSGEP SEEVKEEGGK PQMNSEGEIP SLPSGSQSAK PVSQPRKSTQ
PDVCASPQEK PLRTLFHQPE EEIEDGGLFI PMEEQDNEES EKRRKKKKGT
KRKRDGRGQE GTLAYDLKLD DMLDRTLEDG AKQHNLTAVN VRNILHEVIT
NEHVVAMMKA AISETEDMPM FEPKMTRSKL KEVVEKGVVI PTWNISPIKK
ANEIKPPQFV DIHLEEDDSS DEEYQPDDEE EDETAEESLL ESDVESTASS
PRGAKKSRLR QSSEMTETDE ESGILSEAEK VTTPAIRHIS AEVVPMGPPP
PPKPKQTRDS TFMEKLHAVD EELASSPVCM DSFQPMDDSL IAFRTRSKMP
LKDVPLGQLE AELQAPDITP DMYDPNTADD EDWKMWLGGL MNDDVGNEDE
ADDDDDPEYN FLEDLDEPDT EDFRTDRAVR ITKKEVNELM EELFETFQDE
MGFSNMEDDG PEEEECVAEP RPNFNTPQAL RFEEPLANLL NEQHRTVKEL
FEQLKMKKSS AKQLQEVEKV KPQSEKVHQT LILDPAQRKR LQQQMQQHVQ
LLTQIHLLAT CNPNLNPEAT TTRIFLKELG TFAQSSIALH HQYNPKFQTL
FQPCNLMGAM QLIEDFSTHV SIDCSPHKTV KKTANEFPCL PKQVAWILAT
SKVFMYPELL PVCSLKAKNP QDKIVFTKAE DNLLALGLKH FEGTEFPNPL
ISKYLLTCKT AHQLTVRIKN LNMNRAPDNI IKFYKKTKQL PVLGKCCEEI
QPHQWKPPIE REEHRLPFWL KASLPSIQEE LRHMADGARE VGNMTGTTEI
NSDRSLEKDN LELGSESRYP LLLPKGVVLK LKPVATRFPR KAWRQKRSSV
LKPLLIQPSP SLQPSFNPGK TPARSTHSEA PPSKMVLRIP HPIQPATVLQ
TVPGVPPLGV SGGESFESPA ALPAVPPEAR TSFPLSESQT LLSSAPVPKV
MLPSLAPSKF RKPYVRRRPS KRRGVKASPC MKPAPVIHHP ASVIFTVPAT
TVKIVSLGGG CNMIQPVNAA VAQSPQTIPI TTLLVNPTSF PCPLNQSLVA
SSVSPLIVSG NSVNLPIPST PEDKAHVNVD IACAVADGEN AFQGLEPKLE
PQELSPLSAT VFPKVEHSPG PPLADAECQE GLSENSACRW TVVKTEEGRQ
ALEPLPQGIQ ESLNNPTPGD LEEIVKMEPE EAREEISGSP ERDICDDIKV
EHAVELDTGA PSEELSSAGE VTKQTVLQKE EERSQPTKTP SSSQEPPDEG
TSGTDVNKGS SKNALSSMDP EVRLSSPPGK PEDSSSVDGQ SVGTPVGPET
GGEKNGPEEE EEEDFDDLTQ DEEDEMSSAS EESVLSVPEL QETMEKLTWL
ASERRMSQEG ESEEENSQEE NSEPEEEEEE EAEGMESLQK EDEMTDEAVG
DSAEKPPTFA SPETAPEVET SRTPPGESIK AAGKGRNNHR ARNKRGSRAR
ASKDTSKLLL LYDEDILERD PLREQKDLAF AQAYLTRVRE ALQHIPGKYE
DFLQVIYEFE SSTQRRTAVD LYKSLQILLQ DWPQLLKDFA AFLLPEQALA
CGLFEEQQAF EKSRKFLRQL EICFAENPSH HQKIIKVLQG CADCLPQEIT
ELKTQMWQLL KGHDHLQDEF SIFFDHLRPA ASRMGDFEEI NWTEEKEYEF
DGFEEVALPD VEEEEEPPKI PTASKNKRKK EIGVQNHDKE TEWPDGAKDC
ACSCHEGGPD SKLKKSKRRS CSHCSSKVCD SKSYKSKEPH ELVGSSPHRE
ASPMPGAKEA GQGKDMMEEE APEERESTEA TQSRTVRTTR KGEMPVSAGL
AVGSTLPSPR EVTVTERLLL DGPPPHSPET PQFPPTTGAV LYTVKRNQVG
PEVRSCPKAS PRLQKEREGQ KAVSESEALM LVWDASETEK LPGTVEPPAS
FLSPVSSKTR DAGRRHVSGK PDTQERWLPS SRARVKTRDR TCPVHESPSG
IDTSETSPKA PRGGLAKDSG TQAKGPEGEQ QPKAAEATVC ANNSKVSSTG
EKVVLWTREA DRVILTMCQE QGAQPQTFNI ISQQLGNKTP AEVSHRFREL
MQLFHTACEA SSEDEDDATS TSNADQLSDH GDLLSEEELD E

. . . GON4L . . .

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. . . GON4L . . .

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